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Could L-Serine be a Brain Health Game Changer?

L-serine brain health benefits -- two men playing a game at a picnic table

Why all the buzz about L-serine? Word is beginning to spread about some of the research surrounding L-serine and its many benefits. Although L-serine was originally discovered back in 1865, emerging research shows L-serine may play a crucial role in supporting healthy neurological function as we age.1

How L-Serine Works & L-Serine Benefits

L-serine is an amino acid found in many proteins. Serine is considered non-essential because if adequate amounts are not achieved through the diet, L-serine can be made in the body from glycine.

Its benefits throughout the human body are many and wide-ranging, but it’s known to play an especially important role in helping promote and maintain neurological health as well as protein fatty acid synthesis, RNA and DNA methylation, nervous system function, muscle growth, healthy metabolism, cell proliferation and much more.1

What the Latest Research on L-Serine Says

Emerging research on L-serine suggests that there are potential new and exciting applications for L-serine. A recent article in Fortune profiled research led by ethnobotanist Paul Cox, who studies the way indigenous people use plants in their customs and diet. With his researchers at his nonprofit Brain Chemistry Labs, Cox is studying how the amino acid L-serine may be neuroprotective and play an important role in nervous system health.Research is still ongoing, and recent findings are showing a need for more studies on the effect L-serine in the diet may have for the body and nervous system function.

How to Get L-Serine & Good Sources of L-Serine

Many foods contain L-serine, and some foods have higher concentrations. High-protein foods, including eggs, milk, cheese, a wide variety of seeds, pork, beef, chicken, fish and some spices, provide the highest concentration of L-serine in foods.

L-Serine Content in Foods3
(per 100 grams)

1. Egg, white, dried, stabilized, glucose reduced

6.15

2. Soy protein isolate

4.59

3. Seaweed, spirulina, dried

2.99

4. Gelatins, dry powder, unsweetened

2.60

5. Fish, cod, Atlantic, dried and salted

2.56

6. Parmesan cheese, shredded

2.40

7. Soybeans, mature seeds, raw

2.35

8. Tofu, dried-frozen (koyadofu)

2.25

9. Milk, dry, nonfat, regular, no added vitamin A/D

1.96

10. Hemp seeds, hulled

1.71

11. Pumpkin and squash seed kernels, dried

1.67

12. Beef, top round roast, boneless, cooked, roasted

1.52

13. Peanut butter, smooth style, with salt

1.48

14. Chicken, broilers or fryers, giblets, cooked, fried

1.43

15. Lima beans, large, mature seeds, raw

1.42

16. Mozzarella cheese, part skim milk

1.41

17. Cheddar cheese, sharp, sliced

1.39

18. Cereals ready-to-eat, wheat germ, toasted, plain

1.38

19. Pork, cured, bacon, cooked, baked

1.35

20. Mozzarella cheese, low moisture, part-skim

1.35

21. Pistachio nuts, dry roasted

1.3

22. Egg, yolk, raw, fresh

1.32

23. Lamb, cooked, braised

1.31

24. Pistachio nuts, raw

1.28

25. Kidney beans, all types, mature seeds, raw

1.28

26. Chicken, drumstick, rotisserie, cooked

1.2

27. Peanuts, all types, raw

1.27

28. Turkey, breast, meat only, cooked, roasted

1.24

L-Serine Supplements

L-serine supplements can provide high concentrations of L-serine to help increase daily intake levels. Swanson AjiPure® L-Serine contains 500 mg of high-purity, USP-grade AjiPure® L-Serine per each veggie capsule serving. This pharmaceutical-grade L-serine is produced in a fermentation process by the amino experts at Japan's Ajinomoto, Amino Science LLC, the world leader in pharmaceutical-grade amino acids.

For more ways to support brain and mood health, read Nourish Your Noggin: 13 Best Foods for Brain Health.

Keep your mind sharp with top supplements for cognitive health.  Shop Now

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Lindsey Bristol, Swanson Health Products

 

 




About Lindsey Toth, MS, RD
Registered Dietitian, Swanson Health Products

Lindsey is a nationally recognized registered dietitian and nutritionist with a soft spot for pie. She empowers people to take charge of their health by finding the balance between the pleasure and nourishment in food.

Her philosophy is that you should take care of your body because it’s the only permanent home you have. It’s what inspired her to pursue a career in nutrition and, ultimately, led her to Swanson Health.

Sources

1 Tom J. de Koning, et al. L-Serine in Disease and Development. Biochem. J. (2003) 371, 653–661: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1223326/pdf/12534373.pdf (Accessed 1/30/19).

2 Rick Tetzeli. Could This Radical New Approach to Alzheimer’s Lead to a Breakthrough? Fortune. (2019). http://fortune.com/longform/alzheimers-disease-cure-breakthrough/ (Accessed 1/30/19)

3 United States Department of Agriculture. USDA Food Composition Databases. (Accessed 1/30/19)

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

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