Sometimes dieting and exercise just don’t cut it for people trying to lose weight. Of the many weight-loss supplements on the market, the American Journal of Medicine reports a promising study that found antioxidant alpha lipoic acid (ALA), helped obese people shed pounds when combined with a low-calorie diet.
“This is the first study to show that ALA treatment led to significant weight reduction in human beings,” said lead researchers Eun Hee Koh, MD and Woo Je Lee, MD of the University of Ulsan College of Medicine in Seoul, Korea.
Obesity rates are rising worldwide, along with other obesity-related conditions like heart disease, diabetes, arthritis, and certain cancers. Losing weight can help extend life expectancy and lower the risk for many of these diseases, but weight-loss therapies aren’t always successful and many people end up gaining the weight back again unless they make permanent lifestyle changes.
Based on the promising results of animal studies, Korean researchers decided to put ALA to the test in obese people. During the 20-week trial, 360 men and women were assigned to receive 1,200 mg or 1,800 mg of ALA or placebo. Participants reduced their daily calorie (energy) intake by 600 calories, and followed a diet composed of 55 to 60% carbs, 20 to 25% fat, and 15 to 20% protein.
Over the course of the study, people in both ALA groups dropped a significant amount of weight. By 20 weeks, the average weight loss in the higher ALA group was significantly greater than that in the placebo group, and waist circumference decreased significantly in the higher ALA group compared with placebo.
People with diabetes who were taking 1,800 mg of ALA also noticed a significant drop in their hemoglobin A1c levels, an indicator of long-term blood sugar control.
No severe side effects related to ALA were noted, but some participants reported itching or hives.
While the results of the new study are very promising, more research is needed to determine the optimal amount of ALA and to compare it with prescription weight-loss medications. For now, following these tips can help you reach your ideal weight.
(Am J Med 2011;doi:10.1016/j.am.med.2010.08.005)
Kimberly Beauchamp, ND, received her doctoral degree from Bastyr University, the nation’s premier academic institution for science-based natural medicine. She co-founded South County Naturopaths in Wakefield, RI, where she practiced whole family care with an emphasis on nutritional counseling, herbal medicine, detoxification, and food allergy identification and treatment. Her blog, Eat Happy, helps take the drama out of healthy eating with real food recipes and nutrition news that you can use. Dr. Beauchamp is a regular contributor to Healthnotes Newswire.