

- Potential to promote mood & neural function
- May support joint comfort & mobility
- Enhances liver health & detoxification
Doctor's Best® Double-Strength SAM-e contains 400 mg of active SAMe in each tablet. Doctor's Best utilizes only the highest-quality Italian Soloesse® SAMe, providing slow and targeted release. S-Adenosyl Methionine (SAMe) is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAMe is involved in numerous biochemical reactions in tissues including the liver, joints and brain. SAMe is also required for biosynthesis of critical neurotransmitters and hormones.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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Supplement Facts
Serving Size 1 Tablet
Servings Per Container 30
Amount Per Serving | % Daily Value |
---|---|
SAM-e(S-Adenosyl-L-Methionine disulfate p-toluensulfonate) 400 mg
|
† |
†Daily Value not established.
Other Ingredients: Microcrystalline cellulose, stearic acid, calcium chloride anhydrous, magnesium silicate, magnesium stearate, magnesium hydroxide, flake shellac dewaxed, glycerol, silica, arginine base, sodium alginate, calcium oxide.
Suggested Adult Use: Take 1 tablet daily between meals, or as recommended by a nutritionally-informed physician. Do not chew or crush tablet.
WARNING: Individuals using antidepressant medications should consult with their prescribing physician prior to using this product. Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAM-e. Do not use if pregnant or nursing. May cause gastrointestinal discomfort in a small percentage of people.
Double Strength SAM-e is sealed in blister packs for freshness and stability.
- Non-GMO
- Gluten Free
- Soy Free
- Vegetarian
Soloesse® is a registered trademark of Gnosis SpA.
Ratings and Reviews
Reviews containing references to a state of disease (e.g., pain, aches, inflammation, medicine replacement, cancer, cold/flu, arthritis, depression, insomnia, etc.) cannot be published. We value your input and look forward to hearing about your personal product experiences. Be sure to explain why you like or dislike the product and focus on the product's features. To meet our publishing standards, please refrain from including the following in your review:All reviews are subject to our Terms of Use. We reserve the right to remove non-compliant reviews language. If you wish to comment on product selection, pricing, ordering, delivery or other issues, please contact our customer service.Reviews containing references to a state of disease (e.g., pain, aches, inflammation, medicine replacement, cancer, cold/flu, arthritis, depression, insomnia, etc.) cannot be published. We value your input and look forward to hearing about your personal product experiences. Be sure to explain why you like or dislike the product and focus on the product's features. To meet our publishing standards, please refrain from including the following in your review:
- Language referencing a state of disease (including but not limited to references to pain, aches, inflammation, medicine replacement, cancer, cold/flu, arthritis, depression, insomnia, etc.)
- Obscene or discriminatory language
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- Personal information such as email addresses, phone numbers or physical addresses
All reviews are subject to our Terms of Use. We reserve the right to remove non-compliant reviews language. If you wish to comment on product selection, pricing, ordering, delivery or other issues, please contact our customer service.
Works for me.
Use it more than a week and like how I feel now. It works for me. Will order it again.Dark Pills?
It seems we are getting a random box of darker pills. We have patients bringing them back because they aren't the normal pill they are used to. I plan to contact Doctors Best to inquire about this but not sure if it's a storage/heat/cold issue for you.
We're sorry, this item is out of stock
We recommend SAMe - High Potency as a replacement
- ( 225 )400 mg 30 Tabs
- discounted price$14.24percent discount-25% OFFretail price$18.99