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Doctor's Best

Double-Strength SAMe 400

4.9 out of 5 (10)

Double-Strength SAMe 400

Item: DB106

  • Potential to promote mood & neural function

  • May support joint comfort & mobility

  • Enhances liver health & detoxification

400 mg 30 Tabs

Retail $39.99
In Stock
  • Potential to promote mood & neural function

  • May support joint comfort & mobility

  • Enhances liver health & detoxification

Doctor's Best Double-Strength SAMe 400 contains 400mg of active SAMe in each tablet. Doctor's Best utilizes only the highest quality Italian SAMe available on the market. S-Adenosyl Methionine (SAMe) is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAMe is involved in numerous biochemical reactions in tissues including the liver, joints and brain. SAMe is also required for biosynthesis of critical neurotransmitters and hormones. Sealed in blister packs for freshness and stability. Store product in a cool, dry place to ensure maximum quality. Free of gluten, soy, wheat, yeast and dairy.

Terms and Ingredient Definitions

Supplement Facts

Serving Size 1 Tablet

Servings Per Container 30 servings

  Amount Per Serving %Daily Value
S-Adenosyl Methionine (from 800 mg of SAM-e tosylate disulfate) 400 mg

†Daily Value not established.

Other Ingredients: Cellulose, Methacrylic Acid Copolymer, Glyceryl Behenate, Magnesium Silicate, Triethyl Citrate, Titanium Dioxide, Magnesium Stearate, Mannitol, Glycerol Palmitostearate, Silicon Dioxide, Medium Chain Triglycerides, Sodium Carboxymethyl Starch and Iron Oxide.

The SAMe found in Doctor's Best SAMe 400 mg (Double Strength) is free from yeast, dairy, gluten, soy, wheat, and artificial flavoring

Suggested Adult Use: Take 1 tablet daily away from food, or as recommended by a nutritionally-informed physician. Do not chew or crush tablet.

WARNING: Individuals using antidepressant medications should consult with their prescribing physician prior to using this product. Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAMe. Do not use if pregnant or nursing. May cause gastrointestinal discomfort in a small percentage of people.

Suitable for vegetarians. Contains nothing other than listed ingredients.

Shipping Weight

.14 lbs

Summary of Customer Ratings & Reviews

Customer Ratings & Reviews

Rated 4.9 out of 5 by 10 reviewers.
Rated 5 out of 5 by It WORKS! I do not consume this routinely.The box may last 6mths to 1 yr for my needs.I only WISH that the company could formulate the tablet without fillers binders etc.I have tried other brands but I return to this for efficacy. September 13, 2015
Rated 5 out of 5 by Simply the BEST! I have used various brands of SAMe over the past 15 years. The level of potency seemed to vary significantly with different brands. Doctor's Best is the Most Potent and Effective SAMe that I have ever used! In reading their information brochure enclosed, I came to understand why this is so. What this product is used and prescribed for in Europe makes this a truly remarkable supplement because it can be a real life saver! Thanks Swanson for the great pricing. November 19, 2013
Rated 5 out of 5 by Good for overall feeling. This is a good product for overall feeling. November 15, 2013
Rated 5 out of 5 by SAMe400 I tried this and found it has helped. It takes a few weeks to experience the positive effects. I am on my second box and plan to continue. My attitude towards life is more positive and I feel better. November 5, 2013
Rated 5 out of 5 by SAME 400 There are a number of SAMe products out there, but this one is 400 mg of S-Adenosyl Methionine "from 800 mg of SAM-e tosylate disulfate." What this means is we really ARE getting 400 mg, unlike the products that are not derived from the 800. If the box doesn't say it, you're not getting the amount you think you are. Also, This company has a better price than my local health food stores. May 13, 2013
Rated 5 out of 5 by excellent i have tried several brands and this is one I depend on to keep me in an awesome mood March 7, 2013
Rated 5 out of 5 by Seems to help my mood, especially in winter December 14, 2012
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