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Lee Swanson Research Update
Black Cohosh, St. John's Wort Team Up to Ease Menopausal Symptoms
May 2006
German researchers found that a fixed combination of black cohosh and St. John's wort was able to help alleviate psychological and physical complaints associated with menopause.
In the double-blind, placebo-controlled study, 301 women with menopausal complaints and psychological symptoms were treated with black cohosh and St. John's wort extracts or placebo for 16 weeks. After the treatment period, the mean Menopause Rating Scale score decreased 50% in the treatment group and 19.6% in the placebo group. Similarly, the Hamilton Depression Rating Scale total score decreased 41.8% in the treatment group and 12.7% in the placebo group. There were no major differences between groups regarding adverse events, laboratory values or tolerability.
The researchers concluded the particular combination of black cohosh and St. John's wort was superior to placebo in alleviating both the emotional and physical complaints associated with menopause.
Obstetrics & Gynecology 107:247-255, 2006
