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Lee Swanson Research Update

Blueberries Help Inhibit Formation of Fat Cells

June 2011

In addition to numerous other recently revealed benefits, blueberries may confer an inhibitory effect on the development of adipocytes (fat cells), according to research presented at the Experimental Biology 2011 meeting held in Washington, DC

Texas Woman’s University graduate student Shiwani Moghe, MS, reported the results of an experiment in which three doses of blueberry polyphenols (150, 200 or 250 micrograms per milliliter) were administered to pre-adipocyte tissue cultures derived from mice. The tissue cultures were analyzed for polyphenol effects on adipocyte differentiation, which is the process by which unspecialized cells acquire the features of adipocytes that synthesize and store fat.

Moghe found a dose-dependent effect of blueberry polyphenols on adipocyte differentiation. Compared to control cultures that did not receive polyphenols, those that received the low, middle and high dose showed a 27%, 63% and 74% reduction, respectively, in lipid content, without any significant difference in lipid breakdown observed.

Experimental Biology 2011 meeting, Washington, DC

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