Lee Swanson Research Update

Review Highlights Astaxanthin’s Range of Potential Health Benefits

December 2010

The potential health benefits for astaxanthin, the pink pigment that gives salmon its color, range from possible risk reduction of metabolic syndrome to improved skin health, says a new review published in Molecular Nutrition & Food Research.

Chinese researchers reviewed currently available scientific literature regarding the most significant activities of astaxanthin and stated: "Astaxanthin has been attributed with extraordinary potential for protecting the organism against a wide range of diseases, and has considerable potential and promising applications in human health.

"Numerous studies have shown that astaxanthin has potential health-promoting effects in the prevention and treatment of various diseases such as chromic inflammatory diseases, metabolic syndrome, diabetes, diabetic nephropathy, cardiovascular diseases, gastrointestinal diseases, liver diseases, neurodegenerative diseases, eye diseases, skin diseases, exercise-induced fatigue, male infertility and HgCl(2)-induced acute renal failure."

Commenting on the potential mechanisms, the review concludes: "[The potential protective effects] against various diseases by astaxanthin are likely to involve antioxidant mechanisms including prevention of oxidative damage and cellular necrosis or apoptosis induced by oxidative stress; other potential mechanisms include decreased expression or production of inflammatory mediators and cytokines by suppressing the activation of nuclear factor-kB, decreased expression or production of transforming growth factor-b1, increased levels of circulating adiponectin and insulin sensitivity, decreased activity of the renin-angiotensin system and antimicrobial activity against H. pylori, etc."

Molecular Nutrition & Food Research Published online ahead of print.

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