Lee Swanson Research Update

Saw Palmetto Extract Useful in Treating BPH

September 2004

An analysis of several clinical trials shows that a standardized saw palmetto extract can be successful in treating benign prostatic hyperplasia (BPH). BPH typically reduces urinary flow and increases nighttime urination in men.

Researchers looked at the results of 14 randomized clinical trials and three open-label trials, involving 4,280 patients. The trials were of different size (22-1,100 patients) and different duration (21-720 days). Peak urinary flow rate and nocturnal urination were the two common endpoints.

While analyzing the studies, researchers noted that standardized saw palmetto was associated with a reduction in International Prostate Symptom Score (IPSS) results. Patients saw an increase in peak urinary flow rate and a reduction in the number of nighttime trips to the bathroom.

Researchers concluded that standardized saw palmetto showed "a significant improvement in peak flow rate and reduction in nocturia above placebo, and a five-point reduction in the IPSS," in men with BPH.

British Journal of Urology International93(6):751-756, 2004

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