Lee Swanson Research Update

UC-II™ Reduces Arthritis Symptoms

June 2006

Undenatured type II collagen (as InterHealth Nutraceuticals UC-II™) significantly reduced pain and lameness associated with arthritis in a four-month study conducted on dogs at Murray State University Veterinary College.

Arthritic large-breed dogs were divided into three groups. The control group received no supplementation, group one received one mg per day of UC-II and group two received 10 mg per day of UC-II (equivalent to the recommended human dosage).

Animals given UC-II showed a marked decline in pain and lameness following physical exertion. The 10 mg dose was the most effective. Neither dose produced any side effects or changes in serum chemistry. The study also showed UC-II combined with glucosamine and chondroitin sulfates provided significantly better results than glucosamine plus chondroitin sulfate alone, suggesting a formulation of these ingredients could provide enhanced benefits to joint health sufferers.

“This study provides strong evidence that UC-II can provide significant help for those suffering from joint health problems,” said Ramesh Gupta, Ph.D., head researcher. “It also shows that UC-II can significantly enhance the effects of glucosamine, plus chondroitin sulfate in arthritis sufferers.”

Results of the study were presented at the 44th annual meeting of the Society of Toxicology in New Orleans.

Annual Meeting of the Society of Toxicology 84(S-1):Abs 809, 2005

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