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Lee Swanson Research Update

Omega-3 EFAs May Cut Arthritis Activity in the Spine

March 2007

Treatment with omega-3 essential fatty acids may provide relief for the symptoms of ankylosing spondylitis (AS), a chronic rheumatic condition concentrated in the spine.

AS, also known as Bechterew's disease, Marie Strumpell disease and rheumatoid spondylitis, is a rheumatoid arthritis of the spine that predominantly affects young men. AS produces pain and stiffness as a result of inflammation of the sacroiliac, intervertebral and costovertebral joints. It has also been known to result in complete spinal and thoracic rigidity.

In a study published in the Scandinavian Journal of Rheumatology, 24 patients were randomly selected to receive either a high-dose (4.5 grams per day) or low-dose (1.9 grams per day) omega-3 supplement. Patients were observed for 21 weeks, with evaluations at 7, 14 and 21 weeks.

Eighteen patients completed the study, nine from each group. Patients in the high-dose group "exhibited a significant decrease in disease activity, according to the Bath Ankylosing Disease Activity Index. Some patients in the high-dose group also reported increased mental alertness; this effect was not observed in the low-dose group.

Bjorn Sundstrom, lead researcher in the study, noted: "The present study clearly indicates that patients with Bechterew's disease may benefit from a treatment with omega-3 fatty acids."

Scandinavian Journal of Rheumatology 35(5):359-362, 2006

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