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Lee Swanson Research Update

Green Tea may Help Fight Leukemia

July 2004

Epigallocatechin-3-gallate (EGCG), an active component in green tea, has been shown in the past to help fight certain kinds of cancer. Scientists have now expanded the powers of EGCG to cover leukemia, another form of cancer, according to a study published in the March 2, 2004 online edition of Blood, the journal of The American Society of Hematology.

Once a guarded secret of ancient Chinese herbalists, green tea has made its way to grocery store shelves and kitchen cupboards throughout the world. Green tea is rich in antioxidant polyphenols that help protect the body against damaging free radicals, and EGCG is the major polyphenol in green tea.

In the study, which was conducted by a team of U.S. researchers, EGCG interrupted communication signals needed by cancer cells to survive in eight out of ten patients with B-cell chronic lymphocytic leukemia (CLL), causing the cancer cells to die. CLL is most commonly diagnosed in patients in their mid to late 60s. The authors of the study suggest their findings could lead to nontoxic, better tolerated, EGCG-based therapies for early stage cases of CLL.

www.bloodjournal.org

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