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Daily supplements of the probiotic bacterial strain Lactobacillus casei rhamnosus may promote healthy immune systems in young children, according to research published in the journal Vaccine. The study, undertaken in Taiwan, involved about 1,000 children under the age of five. Working in collaboration with researchers from National Chiao Tung University, Tzu Chi University and National Dong-Hwa University, Dr. Jun-Song Lin recruited 986 children and randomly assigned them to one of four groups: The first received no supplements and acted as the control group. The second group received a daily supplement of L. casei rhamnosus (200 million cfu). The third group received daily supplements of L. rhamnosus T cell-1 (10 billion CFU). The fourth group received a supplement containing 12 bacterial strains. Significant support was observed in the single strain group (1.8 times) and the T cell-1 group (1.92 times). No significant change was noted in the group taking the multiple strain probiotic.
Vaccine 27(7):1073–1079, 2009