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Supplementing with DHA (docosaheaxaenoic acid) could help children with inherited high cholesterol lower their risk of developing heart disease later in life, according to a study carried out at the University of California, San Francisco.
Twenty children, ages 9 to 19, all with hereditary high cholesterol, were first fed a stabilizing low-fat diet for six weeks, and then either a daily dose of 1.2 g of DHA or a placebo. In children taking the DHA supplements, the number of large, buoyant LDL (low-density lipoprotein) and HDL (high-density lipoprotein) particles was significantly increased, while the number of the dangerous small, dense, more atherogenic LDL particles was reduced by 48%.
The American Journal of Cardiology 95(7):869-871, 2005