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"Chromium supplementation seems to improve glycemic control in type 2 diabetic patients, which appears to be due to an increase in insulin action rather than stimulation of insulin secretion." That's the conclusion reached in a study performed by scientists in India.
The double-blind, placebo-controlled, crossover study evaluated the effects of chromium picolinate (400 mcg per day) in 43 people with type 2 diabetes. Significant improvements were seen in fasting glucose levels, post-prandial glucose levels and fasting insulin levels after 12 weeks of chromium administration.
Researchers also looked at the effect of chromium picolinate supplementation on adverse cardiovascular risk, but found nothing conclusive. The change in lipid parameters (total serum cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and triglycerides) did not show significant difference between the chromium and placebo groups.
Journal of Nutritional Biochemistry 13(11):690-697, 2002