Lee Swanson Research Update

Vitamin E May Help Prevent Lou Gehrig's Disease

December 2008

Lou Gehrig

A new study funded by the National Institutes of Health suggests that vitamin E may help prevent amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. Scientists believe oxidative stress may contribute to the cause of ALS and studied whether or not supplementation with vitamin E, a powerful antioxidant, would lower the risk of developing ALS.

The trial involved 957,740 subjects, age 30 or older, who were participating in the American Cancer Society's Prevention Study II. Information on vitamin use had been collected when the subjects were enrolled in the study in 1982. Participants were followed through 1998 to see how many died of ALS.

Researchers found that people who took vitamin E supplements for at least 10 years were 62% less likely than average to die from the disease. Subjects who had taken the vitamin regularly for less than 10 years and subjects who took it occasionally also had a lower risk of dying from ALS than those who did not take vitamin E.

Annals of Neurology 57(1):104-110, 2005

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