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Robert Barry, Ph.D., Scientific Affairs, Kaneka Nutrients, L.P. Dr. Barry earned his Ph.D. from the University of Maryland.
Ubiquinol is the reduced, active form of Coenzyme Q10 (CoQ10). Produced naturally within the body, ubiquinol is CoQ10 that has been converted into the form that is active within our cells.
The body's ability to produce CoQ10 declines with age, as does the ability to convert it into ubiquinol. Ubiquinol levels have been shown to be suppressed in older individuals. Ubiquinone (CoQ10) levels within the body typically begin decreasing as early as age 20, suggesting that it has a close connection with aging. Additionally, the body's ability to convert these declining levels of CoQ10 into ubiquinol is also diminished with age.
As the body begins losing its natural ability to maintain optimal levels of ubiquinone and ubiquinol, the most efficient way to restore healthy levels of these nutrients is through supplementation. For those who are still able to convert ubiquinone to ubiquinol, supplementing with CoQ10 should be sufficient. Ubiquinone will continue to be an important supplement for those in their 20s and 30s. Ubiquinol, however, will be of particular importance for those 40 and older, or those with hindered ability to convert CoQ10. Those who are over 40 years old or suspect their ubiquinol production may be diminished should consider supplementing with ubiquinol (Kaneka QH) to raise their plasma levels most efficiently.