50 years of Research and Innovation—
The History of CoQ10


Year Innovation
1957 Dr. Frederick Crane isolates CoQ10 for the first time from beef heart at the University of Wisconsin. In England, Professor R.A. Morton follows by identifying Q10 in rat liver Morton names the compound "ubiquinone".
1958 Dr. Karl Folkers, working with scientists at Merek, Inc., identifies the exact chemical structure of CoQ10 and develops the first process to synthesize it.
1967-1968 The first clinical research of CoQ10 appears in medical journals.
1972 Dr. Folkers and colleagues in Italy report the first documented evidence of CoQ10 deficiency.
1977 Kaneka manufactures commercially available CoQ10.
1978 Dr. Peter Mitchell wins the Nobel Prize for his work in characterizing the process of biological energy transfer, which includes the role of CoQ10 in energy transfer systems.
1980 Dr. Folkers begins research collaboration with cardiologist Dr. Per H. Langsjoen at Scott & White Memorial Hospital in Temple, Texas. Dr. Langsjoen's son, Peter, joins the research team.
1986 Dr. Folkers is awarded the Priestly Medal by the American Chemical Society for his distinguished work.
1997 Researchers around the world establish the International CoQ10 Association to guide the research and provide a forum for sharing new discoveries with the medical community. Dr. Peter Langsjoen and representatives of Kaneka are founding members.
2007 Kaneka introduces Coenzyme QH, the first stabilized supplemental form of ubiquinol, the reduced form of CoQ10 as it exists in the human body.
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