Pycnogenol is the trademarked name for an extract of the French maritime (Landes) pine tree. This extract is a rich source of flavonoid compounds called proanthocyanidins (also called "OPCs" for oligomeric proanthocyanidins or "PCOs" for procyanidolic oligomers). These compounds have powerful antioxidant properties, which can be very beneficial for cells and tissues throughout the body. Although PCOs are found in a wide variety of plants, the best supplemental sources are Pycnogenol and grapeseed extract. The PCO concentration of Pycnogenol ranges from 80 to 85 percent.
The active components of Pycnogenol are proanthocyanidins (PCOs), which make up 80 to 85 percent of the extract.
For daily antioxidant support, 50 mg of Pycnogenol per day is suitable for most people, although people with special health concerns often take as much as 300 mg per day. Pycnogenol has no known toxicity and is very well tolerated in this dosage range.