Based off of the available literature and research (which can be found in the public domain) we see no indication that someone who is allergic to sulfa drugs could not use MSM. Typically sulfa drugs are not allergenic by themselves, but when a sulfonamide molecule is metabolized in the body, it is capable of attaching to proteins then forming a larger molecule that can serve as an allergen. Sulfa (sulfonamide) drugs do contain sulfur but it is not the sulfur that is the allergenic agent, rather it is when the sulfa drug is metabolized that potential allergenic proteins can be formed. We see no reason why someone could not take MSM if they had a sulfa drug allergy.
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